Author/Authors :
Thirupathi, G Department of Chemistry - Osmania University , Yadaiah Goud, E Department of Chemistry - Osmania University , Hemasri, Y Department of Chemistry - Nizam College - Osmania University , Suban Ali, MD Department of Biochemistry -Sri Venkateswara University , Jayaprakash Rao, Y Department of Chemistry - Osmania University
Abstract :
A facile, convenient, efficient and high-yielding synthesis of 3-aroylcoumarinoflavones has been developed by the condensation of easily synthesized 7-hydroxy-8-formylflavones and benzoyl acetonitriles in the presence of catalytic amount of l-proline in ethanol reflux. All the synthesized compounds were evaluated for their antioxidant activity. Some of the compounds showed very good activity compared to standard BHT.
Keywords :
7-Hydroxyflavones , Duff reaction , Knoevenagel condensation , Antioxidant activity
