Title of article :
Nanocrystalline copper(II) oxide-catalyzed one-pot fourcomponent synthesis of polyhydroquinoline derivativesunder solvent-free conditions
Author/Authors :
Safaei-Ghomi, J Department of Organic Chemistry, Faculty of Chemistry, University of Kashan , Ghasemzadeh, M. A Department of Organic Chemistry, Faculty of Chemistry, University of Kashan
Abstract :
The efficient and environmentally friendly method for the one-pot
synthesis of polyhydroquinolines has been developed in the presence
of CuO nanoparticles. The multi-component reactions of aldehydes,
dimedone, ethyl acetoacetate andammonium acetate were carried out
under solvent-free conditions to afford some polyhydroquinoline
derivatives. This method provides several advantages including high
yields, low reaction times and little catalyst loading.
Keywords :
CuO nanoparticles , Multi-component reactions , Polyhydroquinoline , Solvent-free
Journal title :
Astroparticle Physics
