Author/Authors :
Razavi Ratki, Kazem Department of Radiology, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran , Fallahi, Babak Research Center for Nuclear Medicine, Tehran University of Medical Sciences, Tehran, Iran , Namiranian, Nassim Yazd Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran , Emami-Ardekani, Alireza Research Center for Nuclear Medicine, Tehran University of Medical Sciences, Tehran, Iran , Saghari, Mohsen Research Center for Nuclear Medicine, Tehran University of Medical Sciences, Tehran, Iran , Mirabzadeh, Arash Psychiatric Department and Social Determinants of Health Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran , Fard-Esfahani, Armaghan Research Center for Nuclear Medicine, Tehran University of Medical Sciences, Tehran, Iran , Beiki, Davood Research Center for Nuclear Medicine, Tehran University of Medical Sciences, Tehran, Iran , Eftekhari, Mohammad Research Center for Nuclear Medicine, Tehran University of Medical Sciences, Tehran, Iran , Pooyafard, Farzaneh Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
Abstract :
Introduction: Differentiated thyroid carcinoma (DTC) is associated with excellent prognosis and high survival rates. This study
was conducted to evaluate the influence of baseline and treatment-related factors on the health related quality of life (QoL) in cured
DTC.
Methods: This study was an analytic cross-sectional study on radio-iodine (RAI) treated DTC patients during 2011-2012. The data
on patients’ QoL were recorded using a validated EORTC QLQ-C30 version 3.0. Also a checklist was used to record demographic
data as well as information about the educational, marital and economic status. Duration of follow up, frequency of RAI therapies
and number of surgeries were also recorded. General linear model multivariate analysis of variances (GLM-MANOVA) was used
to analyze the data.
Results: Totally 435 DTC patients, 41.11±11.25 years, 77% female were assessed. Most of them were married (79%) and
unemployed (57%). Global health and Qol as well as functional domains were better in women, single and higher educated patients.
The QoL score in female cases was better in four functional subdomains, i.e physical, emotional, role and cognitive, but not for
social functioning. QoL was adversely affected by increased number of radio-iodine therapies, radio-iodine cumulative doses and
number of surgeries.
Conclusion: We found that quality-of-life scores are affected by the majority of socio-economic, treatment and follow-up
variables. Attention to the quality of life and well-being of the patient as well as availability of professional support may be
important aspects of the DTC patients’ treatment and follow-up.
