Author/Authors :
Jafari, Farnaz Department of Endodontics - Dental School, Tabriz University of Medical Sciences, Tabriz , Jafari, Sanaz Department of Orthodontics - Dental School, Ilam University of Medical Sciences, Ilam , Samadi Kafil, Hossein Drug Applied Research Center - Tabriz University of Medical Sciences, Tabriz , Momeni, Tahereh Dentist - Dental School, Tabriz University of Medical Sciences, Tabriz , Jamloo, Helen Dentist - Dental School, Tabriz University of Medical Sciences, Tabriz
Abstract :
Introduction: Microorganisms and microbial products are the main etiologic factors in
pulp and periapical diseases. The present study aimed to compare the antifungal activity
of two different sealers, AH-26 and MTA Fillapex against three strains of Candida, 24, 48,
72 h and 7 days after mixing. Methods and Materials: The microorganisms used in this
study were Candidia albicans (ATCC 10231), Candidia glabrata (ATCC 90030) and
Candidia krusei (DSM 70079). This test was based on growth of microorganisms and
turbidity measurement technique using a spectrophotometer. The direct contact test was
conducted by direct and indirect methods. Multiple comparisons were carried out using
analysis of variances (ANOVA) with repeated measures followed by Tukey’s tests. Results:
The antifungal activity of both sealers was similar in the indirect method. The antifungal
activity of both sealers in the direct method was similar against Candida albicans and
higher for AH-26 sealer against Candida krusei and Candida glabrata. Conclusion: The
total antifungal effect of MTA Fillapex sealer was significantly less than AH-26 sealer in
direct method. The antifungal effect of both sealers was similar in indirect method.
Keywords :
Antifungal , Antimicrobial , Candida , Endodontic Sealers
