Author/Authors :
ASSMAR, Mehdi Dept. of Parasitology - Pasteur Institute of Iran, Tehran, Iran , KEYPOUR, Marjan Dept. of Epidemiology and Biostatistics - Research Center for Emerging and Reemerging Infectious Diseases - Pasteur Institute of Iran, Tehran, Iran , ROHANI, Mehdi National Reference Laboratory for Plague - Tularemia and Q Fever - Research Centre for Emerging and Reemerging Infectious Diseases - Pasteur Institute of Iran, Hamadan, Iran , MOSTAFAVI, Ehsan Dept. of Epidemiology and Biostatistics - Research Center for Emerging and Reemerging Infectious Diseases - Pasteur Institute of Iran, Tehran, Iran , DANESHVAR FARHUD, Dariush Dept. of Basic Sciences/Ethics - Iranian Academy of Medical Sciences, Tehran, Iran
Abstract :
Background: The present study was conducted approximately 40 years ago, but its results have not been released. At the time of this study, the importance of the gut microbiota was not fully understood. Methods: Meriones persicus rodents, as one of the major reservoirs of Yersinia pestis bacterium in Iran, were compared in a disease endemic area (Akanlu, Hamadan, western Iran) and a non-endemic zone (Telo, Tehran, Iran) from 1977 to1981. Results: This study was able to transmit the resistance to Y. pestis to other rodents creatively by using and transferring gut microbiota. Conclusion: The study indicated for the first time that the gut microbiota could affect the sensitivity to plague in Meriones in Telo.
Keywords :
Gut microbiota , Infectious disease , Meriones persicus , Plague , Iran
