Author/Authors :
ZHANG, Yuanming Dept. of Preventative Medicine, Zhejiang Provincial Key Laboratory of Pathophysiology - School of Medicine - Ningbo University, Ningbo, China , YOU, Dingyun Dept. of Science and Technology - Kunming Medical University, Kunming, China , LU, Nanjia Dept. of Preventative Medicine - Zhejiang Provincial Key Laboratory of Pathophysiology - School of Medicine - Ningbo University, Ningbo, China , DUAN, Donghui Dept. of Preventative Medicine - Zhejiang Provincial Key Laboratory of Pathophysiology - School of Medicine - Ningbo University, Ningbo, China , FENG, Xiaoqi Population Wellbeing and Environment Research Lab (Power Lab) - Faculty of Social Sciences - University of Wollongong, NSW, 2522, Australia , ASTELL-BURT, Thomas Population Wellbeing and Environment Research Lab (Power Lab) - Faculty of Social Sciences - University of Wollongong, NSW, 2522, Australia , ZHU, Pan Dept. of Preventative Medicine - Zhejiang Provincial Key Laboratory of Pathophysiology - School of Medicine - Ningbo University, Ningbo, China , HAN, Liyuan Dept. of Preventative Medicine - Zhejiang Provincial Key Laboratory of Pathophysiology - School of Medicine - Ningbo University, Ningbo, China , DUAN, Shiwei Dept. of Preventative Medicine - Zhejiang Provincial Key Laboratory of Pathophysiology - School of Medicine - Ningbo University, Ningbo, China , ZOU, Zuquan ept. of Preventative Medicine - Zhejiang Provincial Key Laboratory of Pathophysiology - School of Medicine - Ningbo University, Ningbo, China
Abstract :
Background: Evidence of increased type 2 diabetes (T2D) risk associated with potatoes consumption is equivocal. We aimed to perform a meta-analyses on the association between potatoes consumption and T2D risk in prospec-tive cohort studies.
Methods: Studies published prior to 31 Aug 2016 were identified in PubMed, EMBASE, and Web of Science. Pooled relative risks (RR) and 95% confidence intervals (95%CI) based upon the highest vs. lowest category of potatoes consumption in each study were calculated in meta-analysis using random-effects models. Dose-response meta-analysis was fitted using generalized least squares regression in order to quantify the association between po-tatoes consumption and T2D risk.
Results: The pooled RR comparing the highest vs. lowest category of potato consumption was 1.077 (95%CI: 1.005, 1.155). Dose-response meta-analysis revealed T2D risk increased 3.5% (RR=1.035, 95% CI: 1.004-1.067) for additional three serving per week serving of potato. The pooled RR comparing the highest vs. lowest category of French fries consumption was 1.362 (95%CI: 1.004, 1.850). Dose-response meta-analysis indicated T2D risk in-creased 18.7% (RR = 1.187, 95% CI: 1.067-1.321) for additional three serving per week of French fries.
Conclusion: This meta-analysis support a significant positive association between high potatoes consumption and risk of T2D, especially the consumption of French fries.
