Author/Authors :
Tripathi, Sanjeev Kumar Department of Microbiology - Sanjay Gandhi Post Graduate Institute of Medical Sciences - Lucknow, India , Gupta, Prashant Department of Microbiology - King George Medical University - Lucknow, India , Khare, Vineeta Department of Microbiology - Hind Institute of Medical Sciences - Barabanki, India , Chatterjee, Animesh Department of Microbiology - Sanjay Gandhi Post Graduate Institute of Medical Sciences - Lucknow, India , Kumar, Rashmi Department of Pediatrics - King George Medical University - Lucknow, India , Yahiya Khan, Mohammed Department of Biotechnology - Babasahib Bhimrao Ambedkar University - Lucknow, India , N Dhole, Tapan Department of Microbiology - Sanjay Gandhi Post Graduate Institute of Medical Sciences - Lucknow, India
Abstract :
Background and Objectives: Dengue has re-emerged as an important arboviral disease causing significant morbidity. It has become hyperendemic in the Indian subcontinent with all four known dengue serotypes circulating.
Materials and Methods: Multiple sequence alignments and phylogenetic trees of DENV-3 were constructed to determine the extent of the isolated dengue virus genetic heterogeneity and phylogeny.
Results: Sequencing and phylogenetic analysis of the C-prM gene junction revealed an active circulation of a new lineage of DENV-3 (genotype III) in this region of India.
Conclusion: Continuous epidemiological surveillance to monitor the incursion and spread of dengue virus genotypes in this region of India is needed.
