Title of article
Closed- and Open-loop Deep Brain Stimulation: Methods, Challenges, Current and Future Aspects
Author/Authors
Ghasemi, P. Department of Electrical and Computer Engineering - Shahid Beheshti University, Tehran, Iran , Sahraee, T. Department of Electronic Engineering - Tabriz University, Tabriz, Iran , Mohammadi, A. Neuroscience Research Center - Baqiyatallah University of Medical Sciences, Tehran, Iran
Pages
8
From page
209
To page
216
Abstract
Deep brain stimulation (DBS) is known as the most effective technique in the treatment of neurodegenerative diseases, especially Parkinson disease (PD) and epilepsy. Relative healing and effective control of disease symptoms are the most significant reasons for the tangible tendency in use and development of this technology. Nevertheless, more cellular and molecular investigations are required to reveal the detailed
mechanism of DBS. Here, we reviewed the methods, challenges and the ways to overcome the limitations of DBS. Also, challenges in probe fabrication technology, material
selection, related mechanical stability and biocompatibility concerns are discussed. Finally, closed- and open-loop stimulation systems were compared.
Keywords
DBS , Open-loop , Closed-loop , Probe , Parkinson Disease , Neural Interface
Journal title
Astroparticle Physics
Serial Year
2018
Record number
2427030
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