Author/Authors :
Rezaie Keikhaie, Khadije Obstetrics and Gynecology Department - Maternal and Fetal Health Research Center - Zabol University of Medical Sciences, Zabol, Iran , Bazi, Saphora Department of Biology - Payam Noor University, Tehran, Iran , Ghorbani, Saeedeh Department of Biology - Faculty of Science - Payam Noor University of Tehran, Tehran, Iran , Roustakhiz, Javad Higher Educational Complex of Saravan, Saravan, Iran , Shahi, Zahra Department of Microbiology - Islamic Azad University Kerman Branch, Kerman, Iran
Abstract :
Background: The overgrowing resistance of the species of candida toward anti-fungus drugs has necessitated the use of compounds
with antifungal features. Some plants have antimicrobial features due to their polyphenols components. This paper aims
at exploring the anti-fungus effects of Zataria multiflora against Candida albicans.
Methods: A total of 20 g of the dried and pounded leaves of the Zataria multiflora was used and its extract was prepared in the rotary
device. Various concentrations of all extracts were prepared in the 96 cell microplate. MIC and diameter of the inhibitory shield
were measured by dilution method and agar disk, respectively.
Results: The Zataria multiflora extract showed good antifungal effects against Candida albicans sample. Therefore, this plant extract
can replace chemical drugs and be used against candida-caused infection upon completion of this research trend.
Conclusions: In the present study the principles of the extract, different methods of minimuminhibitory concentration (MIC), and
mode of action of the extract are discussed.
Keywords :
Candida albicans , Zataria multiflora , Extract , Antifungal Effects
