Primary Adrenal Insufficiency (Addison’s Disease) Associated with Systemic Lupus Erythematosus: A Rare Occurrence

Coexistence of Addison’s disease and systemic lupus erythematosus (SLE) is a rare occurrence with only few reported cases in the literature. We describe a 29‑year‑old woman who presented to us with clinical features of acute Addisonian crisis and SLE. Laboratory investigations were confirmatory of Addison’s disease in a background of SLE. The patient made remarkable improvement on administration of steroids as replacement therapy for adrenal insufficiency and treatment of SLE. Clinicians need to have a high‑index of suspicion of this possible coexistence in order to avoid the associated deleterious hemodynamic and metabolic consequences.