Title of article :
Green Synthesis of Pyrazol-chromeno[2,3-d]pyrimidinones Using SBA-Pr-SO3H as an Efficient Nanocatalyst
Author/Authors :
Mohammadi Ziarani, Ghodsi Department of Chemistry - Alzahra University - Tehran , Saidian, Fatemeh , Gholamzadeh, Parisa , Badiei, Alireza School of Chemistry, College of Science - University of Tehran - Tehran , Abolhasani Soorki, Ali Research Institute of Petroleum - Shahid Beheshti University Branch - Academic Center for Education - Culture & Research - Tehran
Abstract :
Hexagonal mesoporous silica (SBA-15) was prepared and then functionalized by (3-mercaptopropyl)trimethoxysilane. The obtained 3-mercaptopropyl functionalized SBA-15 (SBA-Pr-SH) was then oxidized using H2O2 in methanol under an acidic condition to give sulfonic acid functionalized mesoporous silica (SBA-Pr-SO3H). The latter was characterized using different techniques (including TGA, BET, BJH, CHN, SEM, and TEM) and then used as a catalyst in organic synthesis. In the next step, SBA-Pr-SO3H catalyzed the three-component reaction of pyrazolone, salicylaldehydes, and barbituric acid in water under reflux condition. Through this procedure various pyrazolchromeno[2,3-d]pyrimidinone derivatives were obtained. The reaction conditions were completely green due to the use of water as a solvent and the presence of an environmentally benign catalyst.
Keywords :
SBA-Pr-SO3H , Green synthesis , Pyrazolone; Barbituric acid , Salicylaldehyde , Multicomponent reactions
Journal title :
Astroparticle Physics
