Author/Authors :
Tajbakhsh, Mahgol Student Research Committee - Mazandaran University of Medical Sciences, Sari , Naalbandi, Hamed Department of Pharmaceutics - Faculty of Pharmacy - Mazandaran University of Medical Sciences, Sari , Saeedi, Majid Department of Pharmaceutics - Faculty of Pharmacy - Mazandaran University of Medical Sciences, Sari , Moharrami Moghanlou, Omid Department of Pharmaceutics - Faculty of Pharmacy - Mazandaran University of Medical Sciences, Sari , Akbari, Jafar Department of Pharmaceutics - Faculty of Pharmacy - Mazandaran University of Medical Sciences, Sari , Morteza-Semnani, Katayoun Department of Medicinal Chemistry - Faculty of Pharmacy - Mazandaran University of Medical Sciences, Sari , Alizadeh, Raouf Central Lab - Vice Chancellor of Food and Drug - Mazandaran University of Medical Sciences, Sari , Esfahani-Zadeh, Mohammad Hossein Central Lab - Vice Chancellor of Food and Drug - Mazandaran University of Medical Sciences, Sari
Abstract :
This study quantitatively estimated heavy metals as cadmium, lead, chromium and nickel (Cd, Pb, Cr and Ni) using flame atomic
absorption spectrometry (FAAS) in ten lipstick products sold by local markets in Sari, Mazandaran State, Iran. All the samples were
digested in HNO3 and HClO4 and then evaluated for heavy metal contents. All the concentrations are mean value of triplicate
experiments for each sample. Analysis of variance (ANOVA) and Tukey post-hoc tests were used to determine significant variations in
heavy metal contents and p < 0.05 was considered as significant. The determined range of cadmium, lead, chromium and nickel were
0.01-0.05 𝜇g /g, 0.18-0.80 𝜇g/g, 0.06-0.75 𝜇g/g, and 0.00-0.34 𝜇g/g, respectively. These results showed that nickel and cadmium
contents were less than WHO and US FDA safe limit, while for chromium only one samples (No. 5) showed higher concentration than
safe limit. The content of lead in all samples were lower than safe limit unless sample 6 which showed high level of lead.
Keywords :
lipstick , nickel , chromium , lead , Cadmium
