Central Corneal Thickness, Corneal Endothelial Cell Density, and Lens Capsule Thickness in Normotensive Patients with and without Pseudoexfoliation Syndrome

Purpose: To compare central corneal thickness (CCT), corneal endothelial cell density, and lens capsule thickness in normotensive patients with and without pseudoexfoliation syndrome (PXS) Methods: This was a prospective, comparative, descriptive study. Normotensive candidates for cataract surgery with (study group) and without (control group) PXS were enrolled in the study. CCT and corneal endothelial cell density were measured preoperatively, and central lens capsule thickness was measured postoperatively. Results: Forty-three eyes of 43 patients in the study group and 39 eyes of 39 age-matched patients in the control group were studied. The mean age was 68.6±11.2 years and 69.3±13.1 years in the PXS and control group, respectively (P=0.5). The mean CCT was 511.9±27.9 μm in the PXS group and 531.4±32.7 μm in the control group (P=0.005). The mean central endothelial cell density was 2045±493 cell/mm2 in the PXS group and 2098±431 cell/mm2 in the control group (P=0.57). In the PXS group, the mean lens capsule thickness was 15.85±3.31 μm, and it was 15.27±3.35 μm in the control group (P=0.4). Conclusion: The mean CCT in PXS group was significantly lower than control group. However, there were no significant differences between corneal endothelial density and anterior lens capsule thickness between PXS group and control group.