Title of article :
A Modified Semiautomatic Method for Measurement of Hyperfluorescence Area in Fluorescein Angiography
Author/Authors :
Naseripour, Masood Eye Research Center - Rassoul Akram Hospital - Iran University of Medical Sciences , Ghasemi Falavarjani, Khalil Eye Research Center - Rassoul Akram Hospital - Iran University of Medical Sciences , Mohammadreza, Hanieh Research Center for Sciences and Technology in Medicine - Tehran University of Medical Sciences , Marjaneh Hejazi, Sedigheh Research Center for Sciences and Technology in Medicine - Tehran University of Medical Sciences
Abstract :
Purpose: To offer a semi-automatic algorithm to determine the area of angiographic
hyperfluorescence
Methods: The proposed algorithm included wavelet filter, histogram equalization and modified Otsu
thresholding. Hyperfluorescent area of 30 angiographic images obtained from patients with leaking
choroidal neovascularization (CNV) and diabetic retinopathy were evaluated and the results were
compared with those obtained by an expert ophthalmologist.
Results: The best wavelet filter was determined. Quantitative assessment of the hyperfluorescent
area showed a mean error of 0.12±0.59 square millimeters. There was no significant difference
between algorithm-measured and ophthalmologist-measured area.
Conclusion: The proposed algorithm may be used to accurately measure area of
hyperfluorescence.
Keywords :
Hyperfluorescence Region , Modified Otsu , Age Related Macular Degeneration , Wavelet Diabetes
Journal title :
Astroparticle Physics
