Central Corneal Thickness in Juvenile Glaucoma

Purpose: To evaluate central corneal thickness (CCT) in patients with juvenile glaucoma and compare it with that of normal individuals Methods: A prospective, case-control study was performed on 80 eyes with juvenile glaucoma who attended glaucoma clinic in Farabi eye hospital, Tehran, Iran and 107 clinically normal healthy eyes. Standard automated perimetry (SAP) was performed for all the participants. CCT was measured using ultrasonic pachymetry. Mean CCT and its correlations with juvenile glaucoma diagnosis, mean deviation (MD) in SAP, age and usage of topical carbonic anhydrase inhibitors (CAIs) was calculated. Results: Mean CCT was 561.6±49.9 μm (range, 463-650 μm) and 531.5±29 μm (range 457-606 μm) in eyes with juvenile glaucoma and normal healthy eyes, respectively. The differences of mean CCT between the groups were highly significant (P<0.001). CCT did not correlate with age, MD and usage of topical CAIs. Conclusion: CCT measurements in eyes with juvenile glaucoma were greater than those in normal healthy eyes. There might be no correlation between CCT and severity of the disease in juvenile glaucoma.