Author/Authors :
Moghimi, Sasan Eye Research Center - Farabi Eye Hospital - Tehran University of Medical Sciences, Tehran , Nazari, Rahman Eye Research Center - Farabi Eye Hospital - Tehran University of Medical Sciences, Tehran , Fakhraie, Ghasem Eye Research Center - Farabi Eye Hospital - Tehran University of Medical Sciences, Tehran , Kiarudi, Mohammad Yaser Eye Research Center - Farabi Eye Hospital - Tehran University of Medical Sciences, Tehran , Eslami, Yadollah Eye Research Center - Farabi Eye Hospital - Tehran University of Medical Sciences, Tehran , Zarei, Reza Eye Research Center - Farabi Eye Hospital - Tehran University of Medical Sciences, Tehran , Zand Vakil, Narges Eye Research Center - Farabi Eye Hospital - Tehran University of Medical Sciences, Tehran , Rafizadeh, Mohsen Eye Research Center - Farabi Eye Hospital - Tehran University of Medical Sciences, Tehran
Abstract :
Purpose: To evaluate central corneal thickness (CCT) in patients with juvenile glaucoma and
compare it with that of normal individuals
Methods: A prospective, case-control study was performed on 80 eyes with juvenile glaucoma who
attended glaucoma clinic in Farabi eye hospital, Tehran, Iran and 107 clinically normal healthy
eyes. Standard automated perimetry (SAP) was performed for all the participants. CCT was
measured using ultrasonic pachymetry. Mean CCT and its correlations with juvenile glaucoma
diagnosis, mean deviation (MD) in SAP, age and usage of topical carbonic anhydrase inhibitors
(CAIs) was calculated.
Results: Mean CCT was 561.6±49.9 μm (range, 463-650 μm) and 531.5±29 μm (range 457-606
μm) in eyes with juvenile glaucoma and normal healthy eyes, respectively. The differences of
mean CCT between the groups were highly significant (P<0.001). CCT did not correlate with age,
MD and usage of topical CAIs.
Conclusion: CCT measurements in eyes with juvenile glaucoma were greater than those in normal
healthy eyes. There might be no correlation between CCT and severity of the disease in juvenile
glaucoma.
