Author/Authors :
Safarpor, F Department of Surgery - Guilan Endocrine and Metabolism Research Center - Razi Hospital , Hedayati Omami, MH Department of Surgery - Guilan Endocrine and Metabolism Research Center - Razi Hospital , Aghajanzadeh, M Department of Surgery - Guilan Endocrine and Metabolism Research Center - Razi Hospital , Mohammadi, F Department of Surgery - Guilan Endocrine and Metabolism Research Center - Razi Hospital , Mehrdad, M Department of Surgery - Guilan Endocrine and Metabolism Research Center - Razi Hospital , Najafi, B Oncology Department - Department of Pathology - General Physician - Guilan University ofMedical Sciences - Rasht 41448, Guilan , Hoda, S Oncology Department - Department of Pathology - General Physician - Guilan University ofMedical Sciences - Rasht 41448, Guilan
Abstract :
Anaplastic thyroid carcinomas are undifferentiated and highly aggressive tumors of the thyroid follicular epithelium,
with a disease-specific mortality approaching 100 percent. This study reports ten cases with advanced
anaplastic thyroid carcinoma with ineffective surgical interventions. Between 2001-2006, we treated 10 patients
with anaplastic carcinoma of the thyroid. All patients presented with advanced phase and were documented by
pathological study. The surgical intervention was thyroidectomy in 3 cases, debunking surgery in other three, just
tracheostomy in three cases, and only biopsy in one patient. All of our patients died in 4 days to 8 months after
surgery. Surgical intervention had no benefit in treatment of advanced anaplastic carcinoma of the thyroid and
the suitable surgical intervention was to maintain an open airway. Early recognition of the disease is essential to
allow prompt initiation of therapy. There is no cure for advanced situations, and surgery, radiotherapy, and chemotherapy
play no important role in the treatment.
