Author/Authors :
Nik, Narieman Department of Ophthalmology and Visual Sciences - Georgetown University/MedStar Washington Hospital Center - Washington - DC, USA , Fong, Amelia Department of Ophthalmology and Visual Sciences - Georgetown University/MedStar Washington Hospital Center - Washington - DC, USA , Derdzakyan, Marianna Silver Spring - Maryland, USA , Adamopoulou, Chrysavgi MetroHealth - Cleveland - Ohio, USA , Sise, Adam Eyecare Medical Group - Portland - Maine, USA , Khanifar, Aziz Retina Group of Washington - Chevy Chase - Maryland, USA , Sanders, Reginald Retina Group of Washington - Chevy Chase - Maryland, USA
Abstract :
Purpose: To assess choroidal perfusion before and after orbital decompression surgery in patients with
Graves’ ophthalmopathy.
Methods: In this interventional case series, surgical decompression for optic nerve compromise was
performed on four eyes of three patients with Graves’ disease. Complete ophthalmic examination including
visual acuity, color vision, and intraocular pressure assessment were done pre‑ and postoperatively.
High‑speed indocyanine green angiography was performed prior to surgery and was repeated one year
after surgery.
Results: In all three patients, choroidal perfusion defects were noted pre‑operatively in the eyes with the
compressive optic neuropathy. At 1 year after orbital decompression surgery, the defects improved or
completely resolved. Improved visual acuity and color perception, as well as decreased intraocular pressure,
were also noted postoperatively.
Conclusion: Patients with Graves’ orbitopathy may have abnormal choroidal perfusion even in the absence
of optic neuropathy. Orbital decompression may improve choroidal circulation in these patients.
Keywords :
Choroid , Circulation , Graves , Indocyanine Green Angiography
