Author/Authors :
Nandeesh, Rudrappa Department of Pharmacognosy - Sree Siddhaganga College of Pharmacy - Tumkur, Karnataka , Kumar, Bagepalli Srinivasa Ashok Department of Pharmacognosy - Sri K.V.College of Pharmacy - Chickballapur - Karnataka, India , Swamy, Vantoor Byrappa Narayana Department of Pharmacognosy - Sri K.V.College of Pharmacy - Chickballapur - Karnataka, India , Lakshman, Kuruba Department of Pharmacognosy - PES College of Pharmacy - Bangaluru - Karnataka, India , Khan, Saleemulla Department of Pharmacognosy - Manipal College of Pharmaceutical Sciences - Manipal - Karnataka, India , Bharathi, Tathireddy Department of Pharmaceutical Biotechnology - Sri Krishan Chaitanya College of Pharmacy - Madanapalle - Andhra Pradesh, India , Ganapathy, Seru Department of Pharmacy - Andhra University - Vishakapatanam - Andhra Pradesh, India
Abstract :
Objective(s)
The aim of this study was to evaluate antioxidant and hair growth activities of Buxus wallichiana Baill
(Buxaceae).
Materials and methods
Petroleum ether, chloroform, methanol and aqueous extracts of Buxus wallichiana subjected to antioxidant
activity by; 2, 2-diphenyl-1-picryl hydrazyl and nitric oxide methods. Methanol extract of Buxus
wallichiana at 50, 100 mg/kg, ointment of methanol extract at 5 and 10% used for the evaluation of hair
growth property.
Results
Methanol extract showed potential antioxidant activity. Methanol extract at 100 mg/kg showed consistent
and significant increase in mean score of hair growth from day 3 to day 24. Whereas 50 mg/kg increased the
mean score significantly, only from day 15 to day 24. When methanol extract at 10% applied topically,
significant increase in mean hair score observed only from day 15, but at 5% showed considerable increase
in mean hair score only from day 21 and 24, when compared to the control.
Conclusion
The result of this study suggests that Methanol extract of Buxus wallichiana possess good antioxidant and
hair growth activity.
