Author/Authors :
Molaei, Amir Department of Mechanical Engineering - Concordia University - Montreal, Canada , Karamzadeh, Vahid Department of Mechanical Engineering - Concordia University - Montreal, Canada , Safi, Sare Shahid Beheshti University of Medical Sciences, Tehran , Esfandiari, Hamed Shahid Beheshti University of Medical Sciences, Tehran , Dargahi, Javad Department of Mechanical Engineering - Concordia University - Montreal, Canada , Khosravi, Mohammad Azam Department of Electrical Engineering - Amirkabir University of Technology, Tehran
Abstract :
Glaucoma is the leading cause of irreversible blindness and vision loss in the world. Although intraocular
pressure (IOP) is no longer considered the only risk factor for glaucoma, it is still the most important one.
In most cases, high IOP is secondary to trabecular meshwork dysfunction. High IOP leads to compaction of
the lamina cribrosa and subsequent damage to retinal ganglion cell axons. Damage to the optic nerve head
is evident on funduscopy as posterior bowing of the lamina cribrosa and increased cupping. Currently,
the only documented method to slow or halt the progression of this disease is to decrease the IOP; hence,
accurate IOP measurement is crucial not only for diagnosis, but also for the management. Due to the dynamic
nature and fluctuation of the IOP, a single clinical measurement is not a reliable indicator of diurnal IOP;
it requires 24‑hour monitoring methods. Technological advances in microelectromechanical systems and
microfluidics provide a promising solution for the effective measurement of IOP. This paper provides a
broad overview of the upcoming technologies to be used for continuous IOP monitoring.
Keywords :
Continuous Monitoring , Glaucoma , Implantable Pressure Sensor , Intraocular Pressure , Microelectromechanical Systems , Microfluidics
