Title of article :
Intravitreal Injection of Anti-vascular Endothelial Growth Factor Agents for Ocular Vascular Diseases: Clinical Practice Guideline
Author/Authors :
Nikkhah, Homayoun Shahid Beheshti University of Medical Sciences, Tehran , Karimi, Saeed Shahid Beheshti University of Medical Sciences, Tehran , Ahmadieh, Hamid Shahid Beheshti University of Medical Sciences, Tehran , Azarmina, Mohsen Shahid Beheshti University of Medical Sciences, Tehran , Abrishami, Majid Department of Ophthalmology - Mashhad University of Medical Sciences, Mashhad , Ahoor, Hossein Department of Ophthalmology - Tabriz University of Medical Sciences, Tabriz , Alizadeh, Yousef Department of Ophthalmology - Guilan University of Medical Sciences, Rasht , Behboudi, Hasan Department of Ophthalmology - Guilan University of Medical Sciences, Rasht , Daftarian, Narsis Shahid Beheshti University of Medical Sciences, Tehran , Dehghan, Mohammad Hossein Shahid Beheshti University of Medical Sciences, Tehran , Entezari, Morteza Shahid Beheshti University of Medical Sciences, Tehran , Farrahi, Fereydoun Department of Ophthalmology - Ahvaz Jundishapur University of Medical Sciences, Ahvaz , Ghanbari, Heshmatollah Department of Ophthalmology - Isfahan University of Medical Sciences, Isfahan , Ghasemi Falavarjani, Khalil Department of Ophthalmology - Rassoul Akram Hospital - Iran University of Medical Sciences, Tehran , Javadi, Mohammad Ali Shahid Beheshti University of Medical Sciences, Tehran , Karkhaneh, Reza Department of Ophthalmology - Farabi Eye Hospital - Tehran University of Medical Sciences, Tehran , Moradian, Siamak Shahid Beheshti University of Medical Sciences, Tehran , Manaviat, Masoud Reza Department of Ophthalmology - Shahid Sadoughi University of Medical Sciences, Yazd , Mehryar, Morsal Department of Ophthalmology - Shiraz University of Medical Sciences, Shiraz , Nourinia, Ramin Shahid Beheshti University of Medical Sciences, Tehran , Mehdi Parvaresh, Mohammad Department of Ophthalmology - Rassoul Akram Hospital - Iran University of Medical Sciences, Tehran , Ramezani, Alireza Shahid Beheshti University of Medical Sciences, Tehran , Ragati Haghi, Alireza Department of Ophthalmology - Razavi Hospital, Mashhad , Riazi‑Esfahani, Mohammad Department of Ophthalmology - Farabi Eye Hospital - Tehran University of Medical Sciences, Tehran , Soheilian, Masoud Shahid Beheshti University of Medical Sciences, Tehran , Shahsavari, Mohsen Department of Ophthalmology - Labbafinejad Medical Center - Shahid Beheshti University of Medical Sciences, Tehran , Shahriari, Hossein-Ali Department of Ophthalmology - Al‑Zahra Eye Center - Zahedan University of Medical Sciences, Zahedan , Rajavi, Zhale Shahid Beheshti University of Medical Sciences, Tehran , Safi, Sare Department of Ophthalmology - Labbafinejad Medical Center - Shahid Beheshti University of Medical Sciences, Tehran , Shirvani, Armin , Rahmani, Saeed Shahid Beheshti University of Medical Sciences, Tehran , Sabbaghi, Hamideh Shahid Beheshti University of Medical Sciences, Tehran , Pakbin, Mojgan Shahid Beheshti University of Medical Sciences, Tehran , Kheiri, Bahareh Shahid Beheshti University of Medical Sciences, Tehran , Ziaei, Hossein Shahid Beheshti University of Medical Sciences, Tehran
Pages :
12
From page :
158
To page :
169
Abstract :
Purpose: To provide the clinical recommendations for the administration of intravitreal anti‑vascular endothelial growth factor (VEGF) drugs especially bavacizumab for ocular vascular diseases including diabetic macular edema, neovascular age‑related macular degeneration, myopic choroidal neovascularization, retinal vein occlusion and central serous chorioretinopathy. Methods: Twenty clinical questions were developed by the guideline technical committee. Relevant websites and databases were searched to find out the pertinent clinical practice guidelines to answer the questions. The technical committee provided possible answers (scenarios) according to the available evidences for each question. All scenarios along with their levels of evidence and the supported articles were sent to the experts for external review. If the experts did not agree on any of the scenarios for one particular clinical question, the technical committee reviewed all scenarios and their pertinent evidences and made the necessary decision. After that, the experts were asked to score them again. All confirmed scenarios were gathered as the final recommendations. Results: All the experts agreed on at least one of the scenarios. The technical committee extracted the agreed scenario for each clinical question as the final recommendation. Finally, 56 recommendations were developed for the procedure of intravitreal anti‑VEGF injection and their applications in the management of ocular vascular diseases. Conclusion: The implementation of this guideline can standardize the management of the common ocular vascular diseases by intravitreal injection of anti‑VEGF agents. It can lead to better policy‑making and evidence‑based clinical decision by ophthalmologists and optimal evidence based eye care for patients.
Keywords :
Age‑related Macular Degeneration , Anti‑vascular Endothelial Growth Factor , Intravitreal Injection , Diabetic Macular Edema , Retinal Vein Occlusion
Journal title :
Astroparticle Physics
Serial Year :
2018
Record number :
2431898
Link To Document :
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