Author/Authors :
Deka, Amarendra Department of Ophthalmology - Mission Nethralaya - Shillong - Meghalaya, India , Siddique, Mir Alam Department of Ophthalmology - Gauhati Medical College - Guwahati - Assam, India , Saikia, Simanta Pradeep Department of Ophthalmology - Mission Nethralaya - Shillong - Meghalaya, India
Abstract :
Purpose: To report three cases of Burkholderia cepacia endophthalmitis following uneventful
phacoemulsification surgery.
Case Report: Three cases presented with blurriness of vision 2 to 3 weeks following phacoemulsification.
Vitreous culture confirmed the diagnosis. Pars plana vitrectomy with intravitreal injection of
vancomycin (1 mg/0.1 ml) and ceftazidime (2.25 mg/0.1 ml) was performed. Despite several modalities of
treatment, 2 cases did not respond to intravitreal antibiotics and vitrectomy. The first case ended up with
phthisis bulbi and the second case underwent evisceration. One case improved after intravitreal injection
of the first dose of antibiotic.
Conclusion: B. cepacia endophthalmitis is rare and difficult to treat. More studies are necessary to understand
the course and outcome of the infection.