Title of article :
Zolpidem dependence, abuse and withdrawal: A case report
Author/Authors :
Heydari, Mostafa Department of Community Medicine - Faculty of Medicine - Baqiyatallah University of Medical Sciences, Tehran , Saberi Isfeedvajani, Mohsen Department of Community Medicine - Faculty of Medicine - Baqiyatallah University of Medical Sciences, Tehran
Abstract :
Zolpidem, a nonbenzodiazepine hypnotic, binds to the benzodiazepine binding site on the gamma-aminobutyric acid type A (GABA-A)
receptors. Many studies have reported efficacy and safety of zolpidem in treatment of insomnia, low abuse, and dependence capability.
However, many cases of zolpidem abuse and dependence were reported around the world. This case showed that zolpidem can exert
abuse capability, euphoric mood, tolerance, and withdrawal syndrome.
Keywords :
Abuse , Dependence , GABA-A receptor Agonists , GABA-A receptor antagonists , substance withdrawal syndrome
Journal title :
Astroparticle Physics
