Preparation and pharmaceutical evaluation of nicotinamide stick for eradication of Staphylococcus epidermidis

Background: Staphylococcus epidermidis is a part of the skin’s normal fl ora that can cause acne. Th is study was designed to evaluate the effi cacy of nicotinamide as a stick in eradication of staphylococcus. Materials and Methods: For evaluating of Anti-microbial eff ect on S. epidermidis used well plate method. We chose fi ve plates for nicotinamide and fi ve for mupirocin. Th e zones of inhibition were measured and compared. Results: Th e results showed nicotinamide stick had anti-microbial eff ects, but in comparison to mupirocin it was signifi cantly less (P = 0.003). Conclusion: Nicotinamide stick was made and evaluated. Th is study showed that nicotinamide had anti-microbial eff ect on staphylococcus.