Abstract :
In this issue of the Journal, two manuscripts are published that are involved with two main perioperative anesthesia challenges:
Perioperative bleeding
Perioperative pain management
Perioperative pain management has been a historical challenge for all the patients (1). As a matter of fact, a number of different aspects are involved in this issue . First of all, the role of pain and its impact on homeostatic functions of the human body has been studied very well; the positive effects of pain control as well. However, there is still a paucity of available clinical pain killers and the current methods, though somewhat effective, lack full satisfaction both for clinicians and the patients (2-6). In this volume of the Journal, Talebi et al have discussed Molecular Mechanisms and Future Perspectives in Perioperative Pain Management (7).