Author/Authors :
Khoshhali, Mehri Tehran University of Medical Sciences, Tehran , Hosseini, Mohsen Department of Biostatistics and Epidemiology - Isfahan University of Medical Sciences , Nilforoushzadeh, Mohammad Ali Tehran University of Medical Sciences, Tehran , Jaffary, Fariba Isfahan University of Medical Sciences, Isfahan , Zolfaghari Baghbaderani, Azadeh Isfahan University of Medical Sciences, Isfahan
Abstract :
Background: The present study was performed to develop a scoring system for predicting cure status in patients with cutaneous
leishmaniasis (CL). Materials and Methods: This study included 199 patients with CL from Skin Diseases and Leishmaniasis
Research Center (Isfahan, Iran). Data were collected as longitudinal in each visit of patients. We applied ordinal logistic generalized
estimating equation regression to predict score on this correlated data. To evaluate the fitted model, split sample validation method
was applied. SPSS software was used for data analysis. Results: The regression coefficients of the fitted model were used to calculate
score for cure status. Based on split‑sample validation method, overall correct classification rate was 82%. Conclusion: This study
suggested a scoring system predict cure status in CL patients based on clinical characteristics. Using this method, score for a CL
patient is easily obtained by physicians or health workers.
Keywords :
Cutaneous leishmaniasis , generalized estimating equation , longitudinal data , scoring system