Erdosteine Therapy for Renal Failure: Current Perspectives

I read the recently published paper of Ebru Uz et al. (1), in the Nephro-Urology Monthly which focused on the renoprotective effects of erdosteine when it is used for cyclosporine-A (CsA) induced chronic nephrotoxicity. Erdosteine belongs to the class of mucolytics which is used for the treatment of wet cough and chronic obstructive pulmonary disease (CoPD). It has been reported that erdosteine possesses multiple mechanisms to protect against hepatic, renal, retinal and cardiotoxicity (2, 3).