Measuring Health Related Quality of Life (Hrqol) in Renal Transplant Patients: Psychometric Properties and Cross-Cultural Adaptation of Kidney Transplant Questionnaire (Ktq-25) in Persian

Background: Different measuring tools have been used to understand the outcomes of renal replacement therapies. The goal of renal transplantation is both to ensure survival, and to promote quality of life in the patients. One of the widely used disease-specific instruments to measure the quality of life is the Kidney Transplant Questionnaire (KTQ-25). Objectives: The current study aimed to perform a cross-cultural adaptation and assess the psychometric properties of the KTQ-25 to Persian. Materials and Methods: The KTQ-25 was trasnlated according to International Quality of Life Assessment (IQOLA) translation methodology. Cronbach’s alpha coefficient, and test-re-test were used to determine internal consistency, and reliability respectively. Results: In the test–re-test reliability of all questionnaire items, Pearson correlation was r = 0.96 (P < 0.001). Cronbach’s alpha coefficient estimated the internal consistency for each scale andalpha equal or more than 0.73 was considered satisfactory. Criterion-related validity, measured by the correlation coefficients between the KTQ-25 and the SF-36 Health Survey, was r = 0.63 (P < 0.001). Conclusions: The psychometric properties of the Kidney Transplant Questionnaire (KTQ-25) in Persian have proven to be satisfactory, therefore the application of this questionnaire in clinical practice can be recommended.