Title of article
Bilateral Laparoscopic Gonadectomy in a Patient With Complete Androgen Insensitivity Syndrome and Bilateral Sertoli-Leydig Cell Tumor: A Case Report and Brief Review of the Literature
Author/Authors
Asl Zare, Mohammad Department of Urology - Faculty of Medicine - Mashhad University of Medical Sciences, Mashhad , Kalantari, Mahmood Reza Department of Pathology - Faculty of Medicine - Mashhad University of Medical Sciences, Mashhad , Asadpour, Amir Abbas Department of Urology - Faculty of Medicine - Mashhad University of Medical Sciences, Mashhad , Kamalati, Ali Department of Urology - Faculty of Medicine - Kerman University of Medical Sciences, Kerman
Pages
5
From page
1
To page
5
Abstract
Introduction: Complete androgen insensitivity syndrome (previously called testicular feminization) is specified by a 46 XY karyotype and negative sex chromatin, bilateral undescended testes, female genitalia appearance, and lack of mullerian derivatives.
Case Presentation: A 28-year-old woman with complete (severe) androgen resistance underwent prophylactic laparoscopic bilateral gonadectomy because of the eventually increased risk of gonadal malignancy. Although the gonads appeared grossly normal, microscopic examination revealed bilateral well differentiated sertoli–leydig cell tumor (SLCT).
Discussion: Our Medline search revealed that this is the first reported case of bilateral sertoli–leydig cell tumor (SLCT) in androgen insensitivity syndrome.
Keywords
Androgen-Insensitivity Syndrome , Sertoli-Leydig Cell Tumor , Laparoscopy
Journal title
Astroparticle Physics
Serial Year
2014
Record number
2433660
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