• Title of article

    ADENYLYL CYCLASE ASSAYS TO MEASURE MACROPHAGE CHEMOTACTIC PROTEIN-1 RECEPTOR FUNCTION

  • Author/Authors

    Qujeq, Durdi Department of Biochemistry and Biophysics - Babol University of Medical Sciences, Babol , Ahmadi, Majid Department of Biochemistry and Biophysics - Babol University of Medical Sciences, Babol

  • Pages
    4
  • From page
    97
  • To page
    100
  • Abstract
    Adenylyl cyclase is a membrane-bound enzyme that catalyzes the conversion of ATP to cAMP. The inhibition of adenylyl cyclase was carried out by measuring the ability of the macrophage chemotactic protein-1 to inhibit the forskoiin-induced enzyme activity. Adenylyl cyclase activity in the presenc of macrophage chemotactic protein-1 was decreased compared to that in controls [2.11+/-0.35 (mean +/- SD.) vs. 6.83 +/- 0.45, activity (/fmol cAMP/mg protein/min) ].
  • Keywords
    Adenylyl cyclase , Macrophage chemotactic protein-1
  • Journal title
    Astroparticle Physics
  • Serial Year
    2000
  • Record number

    2434497

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=2434497