Author/Authors :
Rajabnia Chenari, Mohsen Department of Internal Medicine - Kurdistan University of Medical Sciences, Kurdistan, Iran , Fazeli, Faramarz Department of Urology - Zahedan University of Medical Sciences , Jahantigh, Mehdi Department of Pathology - Zahedan University of Medical Sciences , Dehghan, Javid Department of Community Medicine - Zahedan University of Medical Sciences , Zarghami, Amin Iranshahr University of Medical Sciences, Iranshahr, Iran , Bahadoram, Mohammad Chronic Renal Failure Research Center - Department of Internal Medicine - Faculty of Medicine - Ahvaz Jundishapur University of Medical Sciences , Ghorbani, Ali Student Research Committee - Faculty of Medicine - Ahvaz Jundishapur University of Medical Sciences , Mirshahvalad, Sajedeh Student Research Committee - Babol University of Medical Sciences, Babol, Iran
Abstract :
procedure in the treatment of urinary stones. According to the growing utilization of ESWL as a major method of urinary stone, management and the reports have been reported based on renal tissue damage.
Objectives: We decided to examine the severity of ESWL-induced renal tissue damage and its related factors by monitoring the urinary levels of cytokines.
Patients and Methods: In this study, the urinary samples of 32 patients with urolithiasis were taken before, 24 hours and 14 days after ESWL and interleukin-1ɑ (IL-1a) and interleukin-6 (IL-6) levels were measured by enzyme-linked immunosorbent assay (ELISA) method.
Results: Our findings indicated that there was a significant difference between the urinary levels of both IL-1ɑ and IL-6 in 14 days before and after ESWL.
Conclusion: According to our results, ESWL leads to an inflammatory process in the urinary tract and the inflammation have continuously increased up to 14 days after procedure.
Keywords :
Lithotripsy , Interleukins , Urinary calculi , Inflammation
