Title of article :
A convenient, facile and novel procedure for synthesis 2-amino-5-aryl-1,3,4- oxadiazoles derivatives
Author/Authors :
Patel, Kinjal D. Department of Chemistry - School of Sciences - Gujarat University, Ahmedabad, Gujarat, India. , Vekariya, Rajesh H. Department of Chemistry - School of Sciences - Gujarat University, Ahmedabad, Gujarat, India , Patel, Hitesh D. Department of Chemistry - School of Sciences - Gujarat University, Ahmedabad, Gujarat, India
Abstract :
A convenient and efficient procedure for the synthesis of substituted 2-amino-5-aryl-1,3,4-oxadiazoles has been
achieved by the reaction between isothiocynate, hydrazine hydrate and acid chloride in which cylodesulfurisation was carried
out by Lugol’s reagent (I2/KI) in the presence of sodium hydroxide. All synthesised compounds were characterised by IR,
Mass, 1H-NMR, 13C-NMR and elemental analysis.
Keywords :
Cylodesulfurisation , Efficient synthesis , High yield , Lugol’s reagent (I2/KI)
Journal title :
Astroparticle Physics
