Title of article :
Benzothiazolopyrimidinone through oxidative coupling of catechols and propylthiouracil
Author/Authors :
Sargordan-Arani, Mohsen Department of Chemistry - Faculty of Science - Yadegar-e-Imam Khomeini (RAH), Shahre Rey Branch, Islamic Azad University, Tehran, Iran , Mirza, Behrooz Department of Chemistry - Karaj Branch, Islamic Azad University, Karaj, Iran
Abstract :
Catechol derivatives' chemical oxidation with potassium ferricyanide as an oxidizing agent (Decker oxidation) has been studied in the presence of 6-propyle-2-thiouracil as nucleophile in aqueous media. The results indicated that catechol and its derivatives participate in a 1, 4 Michael addition reaction with 6-propyle-2-thiouracil (ptu) to form the new and novel benzo thiazolopyrimidinone compounds. The chemical synthesis of this compound has been successfully performed at a good yield, characterizedby IR, 1HNMR and 13C NMR and MS spectroscopy.
Keywords :
Propylthiouracil , Catechol , o-benzoquinones , Oxidative coupling , Potassium ferricyanide
Journal title :
Astroparticle Physics
