Author/Authors :
Padwal, Swati Post Graduate Department of Chemistry and Research Centre - Padmashri Vikhe Patil College, Tal- Rahata, Dist- Ahmednagar, India , Ugale, Sandip R. Post Graduate Department of Chemistry and Research Centre - Padmashri Vikhe Patil College, Tal- Rahata, Dist- Ahmednagar, India , Gholap, Somnath S. Post Graduate Department of Chemistry and Research Centre - Padmashri Vikhe Patil College, Tal- Rahata, Dist- Ahmednagar, India
Abstract :
series of structurally diverse aryl/heteroaryl nitriles has been synthesized by ultrasound assisted reaction of aldehydes and hydroxyl amine hydrochloride in dimethyl sulphoxide. Despite of using any acid, base or metal catalyst, the corresponding nitriles are obtained in good to excellent yields with high purity. The methodology presented here is applicable for aromatic or heteroaromatic aldehyde possessing electron donating or electron withdrawing substituents.