Author/Authors :
Rezaei-Chaparpordi, S Dept. of Microbiology - Lahijan Islamic Azad University, Lahijan , Assmar, M Dept. of Microbiology - Lahijan Islamic Azad University, Lahijan , Modiri, L Dept. of Microbiology - Lahijan Islamic Azad University, Lahijan , Massiha, A Dept. of Microbiology - Lahijan Islamic Azad University, Lahijan , Akbari, S Dept. of Microbiology - Lahijan Islamic Azad University, Lahijan , Amirmozafari, N Dept. of Microbiology - Tehran University of Medical Sciences, Tehran, Iran , Shokri-Fashtali, S Dept. of Mathematics - Lahijan Islamic Azad University, Lahijan , Gholizadeh, Z Zist Faravard Pars Company, Rasht, Iran
Abstract :
Background: Herpes simplex virus (HSV) type 1 and 2 are common infectious agents worldwide. Data on prevalence
of HSV-1 and HSV-2 infection are limited in Asia, especially in Iran. The aim of this study was to determine the
seroprevalence of HSV type 1 and 2 based on age, gender, marital status, education, living area, job, symptoms and
history of disease variables.
Methods: The study population included 800 randomly selected persons from laboratories in Gilan Province, Iran,
from 2010 to 2011. Demographic data gathered by a well-designed questionnaire and for serological studies, blood
samples were collected and centrifuged. ELISA HSV-1, 2 and HSV-2 specific ELISA kits were used to determine IgG
type specific antibodies in sera samples. Person's chi-square test was applied to compare HSV-1 and HSV-2
seropositivities.
Results: HSV-1 and HSV-2 IgG antibodies were positive in 467 (58.4%) and 28 (3.5%) subjects, respectively. There
was significant correlation between age, marital status, job, symptoms, history of disease and HSV seroprevalence
(P<0.05).
Conclusion: Our findings were in agreement with prior studies in which HSV-1 infections was more prevalent than
HSV-2 and seropositivity increased with age.
Keywords :
HSV-1 , HSV-2 , ELISA , Prevalence , Iran
