Title of article
Antibacterial Susceptibility Patterns and Cross-Resistance of Acinetobacter, Isolated from Hospitalized Patients, Southern Iran
Author/Authors
Japoni, S Department of Biology - Alzahra University, Tehran , Abdi Ali, A Department of Biology - Alzahra University, Tehran , Farshad, S Professor Alborzi Clinical Microbiology Research Center - Nemazee hospital - Shiraz University of Medical Sciences, Shiraz , Japoni, A Professor Alborzi Clinical Microbiology Research Center - Nemazee hospital - Shiraz University of Medical Sciences, Shiraz
Pages
5
From page
832
To page
836
Abstract
Background: Acinetobacter is a multi-drug resistant and nosocomial pathogen. The aim of this study was to
determine antibacterial susceptibility patterns and cross-resistance of Acinetobacter species.
Methods: This study was conducted in Nemazee Hospital, Shiraz, Iran from October 2007 to September 2008.
Species identification was carried out by API E20. Minimum inhibitory concentration and cross-resistance of the
isolated strains to 12 antibiotics were determined by E-test method.
Results: Eighty eight isolates of Acinetobacter were collected from patients’ samples. Acinetobacter baumannii
was isolated most frequently (79; 89.8%). Colistin, imipenem and meropenem were found to be the three most
effective antibiotics with 97.7%, 77.3% and 72.7% activity against the isolates, respectively. Multi-drug resistance
was revealed among 2 to 11 antibiotics and high cross-resistance was also noticed.
Conclusion: To alleviate the situation, strict control measures and appropriate effective antibiotic therapy should
be adopted to reduce hospital costs and related mortality.
Keywords
Acinetobacter , Antibiotic resistance , Cross resistance , Iran
Journal title
Astroparticle Physics
Serial Year
2011
Record number
2440966
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