Assessment of the Relationship Between the HbA1c Level and Atherosclerosis Burden in Patients Undergoing Coronary Angiography in Farshchian Heart Center, Hamadan, Iran

Background: Diabetes mellitus (DM) is a chronic disease which increases the risk of coronary artery disease (CAD). We sought to determine the relationship between the serum HbA1c level and the severity of CAD in diabetic patients. Methods: This cross-sectional study enrolled 138 patients with DM who were candidated for selective coronary angiography. HbA1C was measured in all the patients. The study population’s demographic information was collected through questionnaires. The data were analyzed with the SPSS software, version 16, and the descriptive statistical method was used to present the results. Results: Selective coronary angiography was normal in 4.3% of the patients, while 26.1% had singlevessel disease, 47.8% had double-vessel disease, and 21.7% had triple-vessel disease. The serum HbA1c was less than 7% in 23.9%, between 7% and 9% in 39.1%, and more than 9% in 36.9% of the patients. A serum HbA1c level of more than 9% was reported in 42.1% of the patients with triple-vessel disease. Conclusions: Our results indicated a relationship between the serum HbA1c level and the severity of CAD.