The Potential of Human Endometrial Stem Cells for Osteoblast Differentiation

The endometrial stem cells were shown to have an excellent pluripotency potential. Human endometrium contains a small population of mesenchymal stem cells (MSC) that may be responsible for its cyclical growth and may provide a readily available source of MSC. However, endometrial stromal cells are easier to isolate and expand with less technical problems compared to bone marrow MSCs. Here we hypothesized that endometrial stem cells may differentiate into osteogenic cells as one of the most important issues in orthopedic surgery associated with bone loss in traumas, infections, tumors or congenital disorders.