Author/Authors :
Hashemi, A Department of Microbiology and Immunology - Mazandaran University of Medical Sciences, Sari , Abediankenari, S Department of Microbiology and Immunology - Mazandaran University of Medical Sciences, Sari , Yousefzadeh, Y Department of Microbiology and Immunology - Mazandaran University of Medical Sciences, Sari , Ghasemi, M Department of Pathology - Mazandaran University of Medical Sciences, Sari , Azadbakht, M Department of Pathology - Mazandaran University of Medical Sciences, Sari , Dehpour, AA Department of Biology - Islamic Azad University - Ghaemshahr Branch, Ghaemshahr, Iran
Abstract :
Background: The therapeutic effect of herbal materials in inhibition of cancer cell growth was shown. This study
investigates the effect of fig tree latex (Ficus carica) on stomach cancer line.
Methods: The in vitro effect of different doses of fig tree latex on stomach cancer cell line and the peripheral
blood mononuclear cells was evaluated after 72 hours.
Results: Fig tree latex could inhibit the proliferation of cancer cell line without any cytotoxic effect on human
normal cells. Five mg/ml was the optimum concentration in inhibition of cell line growth.
Conclusion: Cancer cell line was more sensitive to Ficus carica latex than normal cells. This anticancer activity
might be due to presence of its proteolytic enzymes.
Keywords :
Fig , Ficus carica , Stomach cancer cell line , Latex
