Title of article
Multiplex PCR for Detection of a Successful Pathogen; Acinetobacter baumanni as a Real Threat in Intensive Care Unit of a University Hospital
Author/Authors
Kalantar, Enayatollah Department of Microbiology - School of Medicine - Alborz University of Medical Sciences, Karaj, IR Iran , Madani, Majid Diagnostic Laboratory - Shahid Rajaei Hospital - Alborz University of Medical Sciences, Karaj, IR Iran , Hatami, Amir Diagnostic Laboratory - Shahid Rajaei Hospital - Alborz University of Medical Sciences, Karaj, IR Iran , Dehghan, Mohammad Hossein Department of Biochemistry - School of Medicine - Alborz University of Medical Sciences, Karaj, IR Iran , Ebadi, Monireh Department of Microbiology - School of Medicine - Alborz University of Medical Sciences, Karaj, IR Iran , Nazari, Morteza Diagnostic Laboratory - Shahid Rajaei Hospital - Alborz University of Medical Sciences, Karaj, IR Iran , Saifei, Saber Diagnostic Laboratory - Shahid Rajaei Hospital - Alborz University of Medical Sciences, Karaj, IR Iran , Saedi, Sadegh Diagnostic Laboratory - Shahid Rajaei Hospital - Alborz University of Medical Sciences, Karaj, IR Iran , Marashi, Mahmoud Amin Department of Microbiology - School of Medicine - Alborz University of Medical Sciences, Karaj, IR Iran
Pages
2
From page
23
To page
24
Abstract
Multidrug resistance in Acinetobacter baumannii is a growing public health concern all over the world. In the current study, the isolation and antimicrobial resistance pattern and detection of blaOXA-51 and lpxC genes by multiplex PCR method was performed.
All the isolates demonstrated high levels of resistance rates to amikacin, ciprofloxacin, meropenem, imipenem, ceftriaxone, gentamicin, and colistin. Screening of two resistance genes by multiplex PCR showed that all the isolates contained blaOXA-51 and lpxC genes. As we previously reported, nosocomial infections caused by A. baumannii isolates are a major cause of morbidity and mortality in our hospital.
Keywords
blaOXA-51 and lpxC genes , Multidrug-resistance , Acinetobacter baumanni , Nosocomial infection
Journal title
Astroparticle Physics
Serial Year
2017
Record number
2442545
Link To Document