Author/Authors :
Ferrara, Pietro Department of Pediatric Sciences and Pediatric Neurology - Catholic University - A. Gemelli Hospital - Rome - Italy , Bottaro, Giorgia Department of Pediatric Sciences and Pediatric Neurology - Catholic University - A. Gemelli Hospital - Rome - Italy , Gatto, Antonio Department of Pediatric Sciences and Pediatric Neurology - Catholic University - A. Gemelli Hospital - Rome - Italy , Vitelli, Ottavio Campus Bio-Medico University - Rome - Italy , Liberatore, Pio Department of Pediatric Sciences and Pediatric Neurology - Catholic University - A. Gemelli Hospital - Rome - Italy , Passera, Sofia Department of Pediatric Sciences and Pediatric Neurology - Catholic University - A. Gemelli Hospital - Rome - Italy , Bottaro, Giorgia Campus Bio-Medico University - Rome - Italy , Bufalo, Francesca del Campus Bio-Medico University - Rome - Italy , Martinelli, Diego Department of Pediatric Sciences and Pediatric Neurology - Catholic University - A. Gemelli Hospital - Rome - Italy , Del Re, Maria Department of Pediatric Sciences and Pediatric Neurology - Catholic University - A. Gemelli Hospital - Rome - Italy , Battaglia, Domenica Department of Pediatric Sciences and Pediatric Neurology - Catholic University - A. Gemelli Hospital - Rome - Italy
Abstract :
Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder with a birth incidence of 1:6.000. It can virtually affect any organ system and all racial and ethnic groups. Clinical manifestations of TSC have variable penetrance. Many affected patients come to medical attention because of seizures or dermatological manifestations. Since no single feature of TSC is pathognomonic, an evaluation of all clinical features is necessary. .....
