Author/Authors :
Babazade, Sh Breast Cancer Study Group - Isfahan University of Medical Sciences, Isfahan , Emami, H School of Medicine - Isfahan University of Medical Sciences , Amouheidari, A Medical Education Research Center - Isfahan University of Medical Sciences - Breast Cancer Study Group - Isfahan University of Medical Sciences , Roayaei, M Breast Cancer Study Group - Isfahan University of Medical Sciences, Isfahan , Hassanzade, A School of Public health - Isfahan University of Medical Sciences , Akbari, A Cancer Research Center - Shahid Beheshti University of Medical Sciences, Tehran
Abstract :
Background: To compare the cosmetic results of whole breast radiotherapy
between cobalt 60 and photon 9MegaVolt in patients underwent breast conserving
surgery.
Methods: The patients with breast saving surgery who were treated by whole
breast radiotherapy with either cobalt 60 or photon 9MV between 2001-2006 in
Sayed-al-Shohada hospital entered the study. The cosmetic results were evaluated
by an expert radiation oncologist with definite criteria.
Results: Frothy patients in cobalt 60 group and 43 patients in photon group were
compared, with median follow up of 40.5 months. The patients in photon group had
less telangectasia and discoloration (p=0.018 and p=0.01, respectively). The
consistency of breast in photon group was better (p=0.019), but for fibrosis the
difference was not statistically significant (p=0.055).Overall cosmetic results in
photon group was much better rather than cobalt 60 group (p=0.005). No
recurrences were observed in both groups.
Conclusion: Cosmetic results in group with photon 9MV were superior to cobalt
group, but the effect of these two beam energy on disease free survival (DFS) and
/or overall survival (OS) should be in more consideration.
Keywords :
Breast neoplasm , Breast conserving surgery , Adjuvant radiotherapy , Cosmetic effect