Author/Authors :
Etebarian, Arghavan Department of Oral and Maxillofacial Pathology - School of Dentistry - Alborz University of Medical Sciences - Karaj, Iran , Nili, Fatemeh Pathology Department - Cancer Institute - Imam Khomeini Hospital Complex - Tehran University of Medical Sciences - Tehran, Iran , Soleimani, Vahid Pathology Department - Cancer Institute - Imam Khomeini Hospital Complex - Tehran University of Medical Sciences - Tehran, Iran , Nobari, Niusha Pathology Department - Cancer Institute - Imam Khomeini Hospital Complex - Tehran University of Medical Sciences - Tehran, Iran , Saffar, Hana Pathology Department - Cancer Institute - Imam Khomeini Hospital Complex - Tehran University of Medical Sciences - Tehran, Iran
Abstract :
Introduction: Anaplastic lymphoma kinase-positive (ALK+) anaplastic large cell lymphoma is a rare subtype of non-Hodgkin lymphomas,
which is usually presented as a systemic advanced stage disease. Extranodal involvement is common in skin, bone, soft
tissue, lung and liver. Primary presentation in oral cavity is extremely rare.
Case Presentation: Here, a 28-year-old man with gingival swelling in the left mandibular molar area after tooth extraction and
regional lymphadenopathy is reported. Microscopic examination revealed anaplastic large lymphoid cells with the positive expression
of ALK protein.
Conclusions: Although the overall survival of ALK-positive anaplastic large cell lymphoma is better than other types of T-cell lymphomas,
it is not clear for its oral counterparts
