Author/Authors :
Radpay, Badiozaman Shahid Beheshti University of Medical Sciences , Parsa, Tahereh Shahid Beheshti University of Medical Sciences , Dabir, Shideh Shahid Beheshti University of Medical Sciences , Boloursaz, Mohammadreza Shahid Beheshti University of Medical Sciences , Arbab, Ahmadreza Shahid Beheshti University of Medical Sciences , Tabatabaei, ahmad Shahid Beheshti University of Medical Sciences
Abstract :
Background
Pulmonary alveolar proteinosis (PAP) is a rare disease in children, characterized by intra-alveolar accumulation of large amounts of surfactant proteins, which severely reduce gas exchange. Whole lung lavage (WLL) is the preferred technique for the treatment of severe PAP.
Case Presentation
This report presents nine pediatric cases with advanced PAP who underwent WLL under general anesthesia during a 9 year period. One patient was treated with multiple unilateral WLL without employing cardiopulmonary bypass (CPB) and eight cases were treated by simultaneous lavage of both lungs using partial CPB.
Conclusion
Our experience suggested that partial CPB was useful to support oxygenation during WLL in small children with severe PAP in whom lung separation and selective lavaging of each lung were impracticable.
Keywords :
Pulmonary Alveolar Proteinosis , Children , Cardiopulmonary Bypass , Whole Lung Lavage
