miRNAs in Glioblastoma Multiforme: A Brief Review

miRNAs are endogenous small noncoding RNAs that can regulate many cellular processes. Different expression levels of several miRNAs have been detected in glioblastomas. Function of miRNAs and targets have been well studied in recent years. According to these studies, the role of miRNAs in glioblastoma pathogenesis have been defined. miRNAs have affected many processes in GBM such as apoptosis, proliferation, angiogenesis, invasion and cell cycle regulation. In this review, we summarize the information of different miRNAs functions in glioblastoma.