Primary Localized Vesical Amyloidosis Mimicking Bladder Carcinoma: A Case Report

Amyloidosis of urinary bladder is a rare condition and may be primary or secondary in nature. A case of primary localized vesical amyloidosis (VA) in a 40-yr-old man is described confused with neoplasm by cystoscopic, urographic. Surgical specimens obtained by transurethral resection (TUR) were diagnostic and histologically revealed amyloid deposits in sub-epithelial stroma with chronic inflammatory and giant-cell reaction. Congo-red positivity of the deposit was retained even after pre-treatment with KMnO4, confirming AL protein and primary nature of the amyloidosis.