Author/Authors :
Mobedi, I Department of Medical Parasitology and Mycology - School of Public Health and Health Research - Medical Sciences/University of Tehran , Daee-Ghazvini, F Department of Medical Parasitology and Mycology - School of Public Health and Health Research - Medical Sciences/University of Tehran , Nakhjavani, F. A Department of Microbiology - School of Medicine - Medical Sciences/University of Tehran , Tohidi, R Department of Medical Parasitology and Mycology - School of Public Health and Health Research - Medical Sciences/University of Tehran , Ghazanfari, M Researcher - Medical Sciences/University of Tehran , Agha-Khani, F Researcher - Medical Sciences/University of Tehran , Rasa, S. H Department of Microbiology - School of Medicine - Kashan University of Medical Sciences , Vand Yusefi, J Center of Investigation of Razi Institute Abstract, Tehran
Abstract :
Mycotic infections have been commonly encountered in patients with hematological
malignancies. The current study seeks the prevalence of actinomycete infection in patients suffering
from blood cells malignancies. A hundred and fifty patients with some kinds of blood cells dyscrasia
who underwent the bone marrow aspiration were recruited. In addition to the diagnostic work up,
samples were examined for the presence of actinomycete infections. Twenty one samples were positive
for actinomycete infections. All of them were infected by Actinomyces naeslundii. All the positive
patients were categorized in malignant groups, acute myelocytic leukemia, chronic myelocytic
leukemia, and lymphoma and myelodysplastic syndrome. High incidence of actinomycete infections in
the present study population was interesting. These results can also be suggestive of a pre-malignancy
role for the actinomycosis.
