Author/Authors :
Najafi-Dalui, Mahdi Cardiac Rehabilitation Research Center - Cardiovascular Research Institute - Isfahan University of Medical Sciences, Isfahan, Iran , Shemirani, Hasan Hypertension Research Center - Cardiovascular Research Institute - Isfahan University of Medical Sciences, Isfahan, Iran , Zavar, Reyhaneh Heart Failure Research Center - Cardiovascular Research Institute - Isfahan University of Medical Sciences, Isfahan, Iran , Eghbal, Ali Isfahan Cardiovascular Research Center - Cardiovascular Research Institute - Isfahan University of Medical Sciences, Isfahan, Iran
Abstract :
BACKGROUND: Atrial fibrillation (AF) is the most common tachyarrhythmia and an important
risk factor for thromboembolic stroke. CHA2DS2-VASc score was introduced for assessment of
embolic events and as criteria for starting anticoagulants. This study was performed to evaluate
the left ventricular diastolic dysfunction (LVDD) in patients with non-hemorrhagic stroke and AF.
METHODS: This cross-sectional study consisted of 76 consecutive patients with suspected nonhemorrhagic
stroke referred to the Cardiology Department of Alzahra and Ayatollah Kashani
hospitals in Isfahan, Iran, during 2015-2016. Demographic, anthropometric and clinical
characteristics were evaluated for all patients at baseline. CHA2DS2-VASc score was calculated
for all. All eligible patients underwent transthoracic echocardiogram (TTE) and LVDD was
measured in the patients.
RESULTS: The mean age of the patients was 64.64 ± 5.95 years and 28 subjects (36.8%) were
women. The most common underlying disease in the patients was hypertension (HTN) (65.8%).
Median (range) CHA2DS2-VASc score was 4 (1-7). Four patients (5.3%) had paroxysmal AF and
16 cases (21.1%) had LVDD. Analysis showed that LVDD in patients with non-hemorrhagic
stroke and coexisting AF was not associated with CHA2DS2-VASc score (r = 0.151, P = 0.192).
CONCLUSION: LVDD is not associated with CHA2DS2-VASc score in patients with nonhemorrhagic
stroke and coexisting AF.
