Title of article :
Botulism Outbreak in a Family after Ingestion of Locally Produced Cheese
Author/Authors :
Rafie, Shahram Department of Neurology - School of Medicine - Ahvaz Jundishapur University of Medical Sciences - Ahvaz , Mehramiri, Asieh Department of Neurology - School of Medicine - Ahvaz Jundishapur University of Medical Sciences - Ahvaz , Nejati, Adel Department of Neurology - School of Medicine - Ahvaz Jundishapur University of Medical Sciences - Ahvaz , Salmanzadeh, Shokrollah Department of Infectious Diseases - School of Medicine - Ahvaz Jundishapur University of Medical Sciences, Ahvaz
Abstract :
Botulism is one of the most important foodborne diseases and is
caused by Clostridium botulinum toxin. The main manifestations
are flaccid muscle paralysis and cranial nerve palsies. Botulism
is an essential health problem because of its high mortality. The
diagnosis of botulism, especially in sporadic cases, is a medical
challenge and a high clinical suspicion is necessary for early
recognition. So, every physician should be familiar with its signs
and symptoms for early detection and treatment. We describe a
family with dysphasia and acute paralysis after the ingestion of
locally made cheese. The clinical presentations of the 1st patient
were similar to myasthenic crisis and she, therefore, received
plasma exchange. After the appearance of similar symptoms in
the other family members, they were treated with polyvalent
botulinum antitoxin and diagnosis was confirmed by toxicology
and detection of serotype A botulinum toxin in cheese and
stool samples. Uncommon clinical presentations and unusual
sources of botulinum toxin should be kept in mind because of
the importance of early diagnosis and treatment.
Keywords :
Botulism , Botulinum toxin A , Cheese
Journal title :
Astroparticle Physics