Author/Authors :
Kazemisaleh, Davoud Atherosclerosis Research Center - Baqiyatallah University of Medical Sciences, Tehran, Iran , Kiani, Keivan Hypertension Research Center - Cardiovascular Research Institute - Isfahan University of Medical Sciences, Isfahan, Iran , Sadeghi, Masoumeh Cardiac Rehabilitation Research Center - Cardiovascular Research Institute - Isfahan University of Medical Sciences, Isfahan, Iran , Roohafza, Hamidreza Psychosomatic Research Center - Isfahan University of Medical Sciences, Isfahan, Iran , Dianatkhah, Minoo Heart Failure Research Center - Cardiovascular Research Institute - Isfahan University of Medical Sciences, Isfahan, Iran , Sarrafzadegan, Nizal Isfahan Cardiovascular Research Center - Cardiovascular Research Institute - Isfahan University of Medical Sciences, Isfahan, Iran
Abstract :
BACKGROUND: Vitamin D deficiency is a prevalent condition in Iran and previous studies have
shown that a low level of serum vitamin D is related to low ankle-brachial index (ABI). In the
present study, the relationship of the serum level of vitamin D with ABI, as an index for
atherosclerosis of peripheral arteries, was evaluated.
METHODS: In this cross-sectional study, data on 91 patients with metabolic syndrome (Mets)
from the Isfahan Cohort Study (ICS) were analyzed in order to evaluate the association between
serum 25(OH) vitamin D level and ABI. The participants were divided into two groups; group A
with desirable serum vitamin D level and group B with abnormal serum vitamin D level. ABI
was measured and compared between these groups.
RESULTS: A crude and adjusted model showed no association between vitamin D level and ABI
in patients with MetS.
CONCLUSION: It can be concluded that serum vitamin D level could not affect ABI in patients
with MetS.