Author/Authors :
Sarrami, Amir Hossein Medical Student - School of Medicine, Isfahan University of Medical Sciences , Setareh, Mehrdad Legal Medicine Specialist - Legal Medicine Center of Isfahan , Afshar-Moghaddam, Noushin Associate Professor - Department of Pathology - School of Medicine, Isfahan University of Medical Sciences , Izadinejad, Masoud Pathologist - Legal Medicine Center of Isfahan , Saadatnia, Mohammad Assistant Professor, Isfahan Neurosciences Research Center, Isfahan University of Medical Sciences
Abstract :
We describe a case of intracranial malignant fibrous histiocytoma which had infiltrated pons, cerebellum and basal surface
of left temporal lobe without any visible mass. The patient presented with a sudden loss of consciousness and vomiting.
Clinical findings, laboratory tests, imaging and examination of the cerebrospinal fluid tended to establish the diagnosis
of an infectious condition than a malignancy. Without any response to the antibiotics and with a progressive
deterioration of neurologic and mental condition, the patient died after 20 days. In the autopsy, histological and immunohistochemical
study of the brain revealed the diagnosis of malignant fibrous histiocytoma (MFH).
Keywords :
Malignant Fibrous Histiocytoma , Central Nervous System , Immunohistochemistry , Sarcoma , Autopsy
